Top 10 Pharmaceutical Companies

1. Pfizer

Pfizer is a research-based global pharmaceutical company. Pfizer discovers, develops, manufactures and markets leading prescription medicines for humans and animals, as well as many of the world's best-known consumer products.

Pfizer now ranks as the largest supplier of medicines to the NHS. Through the pharmaceutical division it markets a wide range of prescription-only medicines which bring relief from suffering in a variety of diseases including infections, arthritis, depression, hypertension and other heart disorders, as well as certain types of cancer.

Top 50 pharmaceutical products:
Lipitor (1), Istin (12), Viagra (23), Lustral (25)

Other Pfizer pharmaceutical products include:
Aricept®, Aromasin®, Caduet®, Camptosar®, Celebrex®, ChantixTM Detrol®, LA Ellence®, Exubera®, Genotropin®, Geodon®, Lipitor®, Lyrica®, Macugen®, Neurontin®, Norvasc®, Rebif®, Relpax®, Spiriva®, Sutent®, Viagra®, Xalatan®, Zoloft® & Zyrtec®.

Pfizer, further information:
www.Pfizer.co.uk, www.Pfizer.com

2. GlaxoSmithKline

GlaxoSmithKline is a research based pharmaceutical company employing over 100,000 people in 116 countries, of whom, over 15,000 are employed in pharmaceutical research. GlaxoSmithKline is currently the only pharmaceutical cmpany in the world to tackle the three priority diseases defined by the World Health Organisation: HIV, tuberculosis and malaria.

GlaxoSmithKline has it's headquarters in the United Kingdom, along with operations in the US. GlaxoSmithKline has an estimated 7% of the worlds pharmaceutical market. GlaxoSmithKline is primarily involved with the disease areas of asthma, virus control, infections, mental health, diabetes, HIV, cancer, malaria, migraine and digestive conditions.

Top 50 pharmaceutical products:
Seretide (2), Serevent (13), Lamictal (31), Avandia (32), Nicorette (40), Flixotide (43), Imigran (44),

Other GlaxoSmithKline pharmaceutical products include:
Adartrel (ropinirole hydrochloride), Agenerase (amprenavir), Alkeran (melphalan), Amoxil (amoxicillin), Andropatch (testosterone), Arixtra (fondaparinux sodium), Augmentin (amoxicillin/clavulanate potassium), Avandia (rosiglitazone maleate), Avodart (dutasteride), Bactroban (mupirocin), Becloforte (beclomethasone dipropionate), Becodisks (beclomethasone dipropionate), Beconase Aq. Nasal Spray (beclomethasone dipropionate), Becotide Inhaler (beclomethasone dipropionate), Betnovate (betamethasone valerate), Cicatrin (neomycin sulphate), Combivir (zidovudine and lamivudine), Cutivate (fluticasone propionate), Daraprim (pyrimethamine), Dermovate (clobetasol propionate), Doralese Tiltab (indoramin hydrochloride), Efcortelan (hydrocortisone), Epivir (lamivudine), Eumovate (clobetasone butyrate), Flixonase (fluticasone propionate), Flixotide (fluticasone propionate), Flolan (epoprostenol), Floxapen (flucloxacillin), Fortum injection (ceftazidime), Imigran (sumatriptan succinate), Imuran (azathioprine), Kivexa (abacavir/lamivudine), Lamictal tablets (lamotrigine), Lanoxin (digoxin), Lanvis (tioguanine), Leukeran (chlorambucil), Liskonum (lithium carbonate), Malarone (atovaquone and proguanil hydrochloride), Mivacron (mivacurium chloride), Naramig (naratriptan hydrochloride), Nimbex (cisatracurium besilate), Otosporin ear drops (polymyxin B sulphate, neomycin sulphate, hydrocortisone), Pentostam (sodium stibogluconate), Propaderm (beclometasone dipropionate), Puri-Nethol (mercaptopurine), Pylorid (ranitidine bismuth citrate), Relenza (zanamivir), Requip tablets (ropinirole hydrochloride), Respontin (nebules ipratropium bromide), Retrovir (zidovudine), Semprex (acrivastine), Septrin (co-trimoxazole), Seretide (salmeterol xinofoate, fluticasone propionate), Serevent (salmeterol xinafoate Seroxat paroxetine hydrochloride), Tagamet (cimetidine), Telzir (fosamprenavir), Timentin (ticarcillin disodium / potassium clavulanate), Tracrium (atracurium besilate), Trimovate (clobetasone butyrate), Trizivir (abacavir sulfate/ lamivudine/zidovudine), Ultiva (remifentanil hydrochloride), Valtrex (valaciclovir hydrochloride), Ventodisks (salbutamol sulphate), Ventolin (salbutamol sulphate), Volmax (salbutamol sulphate), Wellvone (atovaquone), Zantac (ranitidine hydrochloride), Zeffix (lamivudine), Ziagen (abacavir sulfate), Zinacef (cefuroxime), Zinnat (cefuroxime axetil), Zofran (ondansetron hydrochloride), Zovirax (aciclovir), Zyban (bupropion hydrochloride), Zyloric (allopurinol).

GlaxoSmithKline, further information:
www.gsk.com

3. Sanofi Aventis

Sanofi-aventis is a leading global pharmaceutical company with primary interests in cardiovascular medicine thrombosis oncology internal medicine metabolic disorders diseases of the central nervous system vaccines. Global headquarters are located in Paris, France and the U.K. headquarters are in Guildford, Surrey.

Top 50 pharmaceutical products:
Plavix (4), Lantus (28), Clexane (35)

Other Sanofi Aventis pharmaceutical products include:
Aprovel (Irbesartan), CoAprovel (Irbesartan/ Hydrochlorothiazide), Copaxone (Glatiramer acetate), Depakote (Valproate Semisodium), Epilim (Sodium Valproate), Epilim Chrono Sodium Valproate/Valproic Acid(), Solian (Amisulpride), Eloxatin (Oxaliplatin), Fasturtec (Rasburicase), Taxotere (Docetaxel), Acomplia (Rimonabant), Amaryl (Glimepiride), Apidra (Insulin Glulisine), Lantus (Insulin Glargine), Actonel (Risedronate Sodium), Targocid (Teicoplanin), Tavanic (Levofloxacin), Telfast (Fexofenadine), Xatral (Alfuzosin).

Sanofi Aventis, further information:
en.sanofi-aventis.com, www.sanofi-aventis.co.uk

4. Wyeth

Established in Philadelphia in the 1860s, Wyeth is now one of the top five largest pharmaceutical companies in the UK in terms of sales to the National Health Service, employing over 2000 people in the UK and 50,000 worldwide. Wyeth has primary interests in: mental health, female health, oncology, gastrointestinal disease, rheumatology, dermatology, infectious disease, transplantation, haemophilia and vaccines.

Top 50 pharmaceutical products:
Zoton (3), Efexor (8), Enbrel (9), Zoton Fastab (22)

Other Wyeth pharmaceutical products include:
Agrippal, Ativan Injection (Lorazepam), Begrivac, Efexor (Venlafaxine), Efexor XL (Venlafaxine) Enbrel (Etanercept), Enbrel 50mg (Etanercept), Heliclear (Lansoprazole/clarithromycin/amoxycillin), InductOs 12mg (Dibotermin alfa), Isovorin (Calcium levofolinate) Lederfolin Solution (Calcium leucovorin), Meningitec (Meningococcal group C conjugate vaccine), Minocin MR (Minocycline), Minulet (Ethinylestradiol/gestodene), Nipent (Pentostatin), Novatrone Injection (Mitoxantrone), Ovranette (Ethinylestradiol/levonorgestrel), Premarin Tablets (Conjugated oestrogens), Premarin Vaginal Cream (Conjugated oestrogens), Premique (Conjugated oestrogens/medroxyprogesterone), Premique Low Dose (Conjugated oestrogens/medroxyprogesterone), Prempak - C (Conjugated oestrogens/norgestrel), Prevenar (Pneumococcal saccharide conjugate vaccine), Prostap 3 (Leuprorelin), Prostap SR (Leuprorelin), Rapamune (Sirolimus), Refacto (Moroctocog alfa), Sonata 5 & 10mg hard capsules (Zaleplon), Tazocin (Tazobactam/piperacillin), Thiotepa Injection 15mg/ml (Thiotepa), Tri-Minulet (Ethinylestadiol/gestrodene), Trinordiol (Ethinylestadiol/levonorgestrel), Tygacil (Tigecycline), Varidase (Streptokinase/streptodornase), Zoton FasTab (Lansoprazole), Zoton Suspension 30mg (Lansoprazole).

Wyeth, further information:
www.wyeth.com, www.wyeth.co.uk

5. AstraZeneca

AstraZeneca is one of the world's leading pharmaceutical companies, dedicated to the discovery, development, manufacturing and marketing of high quality, effective prescription medicines and with a primary focus on cancer, cardiovascular, gastrointestinal, infection, neuroscience and respiratory & inflammation. AstraZeneca employ around 12,000 people in research and development, 14,000 people at 27 manufacturing sites and a total of 65,000 people worldwide. Corporate headquarters are in London, UK.

Top 50 pharmaceutical products:
Seroquel (20), Zoladex (21), Nexium (26), Crestor (42), Arimidex (46), Casodex (47), Aprovel (48), Pulmicort (50)

Other AstraZeneca pharmaceutical products include:
Accolate, Accoleit, Vanticon (zafirlukast), Arimidex (anastrozole), Atacand (candesartan cilexetil), Bambec, Oxeol (bambuterol), Bricanyl (terbutaline), Carbocaine (mepivacaine), Casodex, Cosudex (bicalutamide), Citanest (prilocaine), Crestor (rosuvastatin), Diprivan (propofol), Entocort (budesonide), Exanta (ximelagatran), Faslodex (fulvestrant), Iressa (gefitinib, ZD1839), Lexxel (enalapril maleate - felodipine), Logimax (felodipine - metoprolol), Losec, Antra, Gastroloc, Mopral, Omepral, Prilosec (omeprazole), Marcaine/Sensorcaine (bupivacaine), Merrem/Meronem (meropenem), Mysoline, Mylepsinum (primidone), Naropin (ropivacaine), Nexium (esomeprazole), Nif-Ten, Tenif, Tenordate (atenolol - nifedipine), Nolvadex, Istubal, Valodex (tamoxifen citrate), Oxis (formoterol), Plendil, Modip, Splendil, Munobal, Flodil (felodipine), Pulmicort, Spirocort (budesonide), Ramace, Hypren, Pramace, Unipril, Vesdil (ramipril), Rhinocort (budesonide), Seroquel (quetiapine), Symbicort (budesonide/formoterol), Tenoretic, Tenoret 50 (atenolol-chlorthalidone), Tenormin, Tenormine, Prenormine, Atenol (atenolol), Tomudex (raltitrexed), Unimax, Inotens, Unimest, Unitens (felodipine - ramipril), Vivalan (viloxazine hydrocholoride), Xylocaine (lidocaine), Zestoretic (lisinopril dihydrate - hydrochlorothiazide), Zestril (lisinopril dihydrate ), Zoladex (goserelin acetate), Zomig, Zomig Rapimelt, Zomig Nasal Spray, AscoTop, Zomigon (zolmitriptan).

AstraZeneca, further information:
www.astrazeneca.com/, www.astrazeneca.co.uk/

6. Novartis

Novartis Pharmaceuticals has primary interests in the following therapeutic areas: General Medicines: Respiratory & Dermatology, Neuroscience, Cardiovascular & Metabolism, AGBHI (Arthritis, Gastrointestinal, Bone, Hormone replacement therapies, Infectious diseases). Novartis is has three business divisions - Pharmaceuticals, Consumer Health and Sandoz (generics divison). With headquarters in Basle, Switzerland, Novartis has their headquarters in Basle, Switzerland and employs 81,000 people worldwide.

Top 50 pharmaceutical products:
Diovan (37), Glivec (38)

Other Novartis pharmaceutical products include:
Anafranil, Anturan (sulfinpyrazone), Apresoline, Aredia (pamidronate disodium), Cafergot (ergotamine tartrate and caffeine, USP), Climagest (oestrodiol and norethisterone), Climesse (oestrodiol and norethisterone), Climaval (oestrodiol), Clozaril (clozapine tablets), Co-Diovan (valsartan, hydrochlorothiazide), Deseril (methysergide), Desferal (chelating agent-deferrioxamine methanesulphonate, USP), Diovan (valsartan), Elidel (nonsteriod anti-inflammatory dermatological cream-pimecrolimus cream, 1%), Estracombi TTS (oestradiol, norethisterone), Estraderm MX / Estraderm® TTS (oestradiol), Exelon (rivastigmine tartrate), Famvir (famciclovir), Femara (letrozole), Foradil Aerolizer™ (formoterol fumerate inhalation powder), Glivec (imatinib mesylate), Hydergine (codergocrine), Hygroton (chlorthalidone), Hypotears (polyvinylalcohol), Lamisil (terbinafine hydrochloride), Lamprene (clofazimine), Lescol / XL (fluvastatin sodium - HMG-CoA reductase inhibitor), Lioresal (baclofen), Loiresal Intrathecal (baclofen), Livostin (Levocabastine hydrochloride), Lopresor (metoprolol tartrate, USP), Ludiomil (maprotiline hydrochloride, methane sulphonate), Melleril (thioridazine HCl, USP-neuroloptic), Metopirone (metyrapone-adrenocorticostatic agent), Miacalcic (synthetic salmon calcitonin-regulator of calcium homeostasis), Miochol (acetylcholine chloride), Myfortic , Navoban (tropisetron HCI), Navispare (cyclopenthiazide and amiloride), Neoral (cyclosporine, USP), Norprolac (quinagolide hydrochloride), Nyogel (timolol), Orimeten (aminoglutethimide), Oculotect (Povidone), Parlodel (bromocriptine mesylate, USP), Prescal (isradipine-calcium antagonist), Regitin (phentolamine methanesulfonate-adrenergic receptor blocker), Riamet (artemether, lumefantrine-blood schizonticide), Ritalin Hydrochloride (methylphenidate hydrochloride tablets, USP), Salagen (pilocarpine), Sandimmun (cyclosporine, USP), s Sanomigran (pizotifen), Sandostatin / LAR (octreotide acetate), Simulect (basiliximab), Sintrome (acenocoumarol), Starlix (nateglinide), Symmetrel (amantadine HCI), Synacthen, (tetracosactide hexaacetate), Syntocinon (synthetic oxytocin), Tegretol / Retard (carbamazepine), Tofranil (imipramine hydrochloride, pamoate-tricyclic antidepressant), Nitro TTS (nitroglycerin-vasodilator), Trasicor (oxprenolol-cardioprotective ß-blocker), Trasidrex® (cyclopenthiazide and oxprenolol), on Trileptal (oxcarbazepine), Viscotears (Carbomer), Viskaldix (pindolol, clopamide), Visken (pidolol-B-adrenoreceptor blocking agent), Visudyne (verteporfin), Voltarol / SR / Retard (diclofenac sodium - non steroidal anti-inflammatory agent), Voltarol / Rapid (diclofenac potassium), Voltarol / Ophtha, Zaditen (ketotifen-asthma prophylactic and antiallergic agent), Zometa (zoledronic acid).

Novartis, further information:
www.novartis.com, http://www.novartis.co.uk

7. Roche

Roche is a world leading healthcare company and for more than 100 years, Roche has been active in the discovery, development, manufacture and marketing of novel healthcare solutions. Roche has two divisions: Pharmaceuticals & Diagnostics. Roche has primary interests in Anaemia, Cardiovascular diseases, Central nervous system, Dermatology, Infectious disease,s Inflammatory and autoimmune diseases, Metabolic disorders, Cancer, Respiratory diseases, Transplantation and Virology. Roche employs roughly 74,000 people in 150 countries.

Top 50 pharmaceutical products:
Mabthera (41),

Other Roche pharmaceutical products include:
Anaprox (Naproxen Sodium), Avastin (Bevacizumab), Bactrim (Sulfamethoxazole trimethoprim), Bezalip (Bezafibrate), Bondronat (Ibandronate), Bonviva (Ibandronate), CellCept (Mycophenolate Mofetil), Fuzeon (Enfuvirtide), Herceptin (Trastuzumab), Invirase (Saquinavir), Kytril (Granisetron HCI), Lariam (Mefloquine), MabThera (Rituximab), MabTheraRA (Rituximab), Madopar (Levodopa), Naprosyn (Naproxen), NeoRecormon (Epoetin beta), Neotigason (Acitetrin), Neulastim (Pegfilgrastim), interferon, Roaccutane (Isotretinoin), Rocaltrol (Calcitriol), Rocephin (Ceftriaxone), Roferon-A (Interferon alfa-2a), Tamiflu (Oseltamivir), Tarceva (Erlotinib), Toradol (Ketorolac), Torem (Torasemide), Valcyte (Valganciclovir), Valium (Diazepam), Vesanoid (Tretinoin), Viracept (Nelfinavir), Xeloda (Capecitabine), Xenical (Orlistat), Zenapax (Daclizumab).

Roche, further information:
www.roche.com

8. Merck Sharp & Dohme

Established in 1891, Merck & Co., Inc. is a global research-driven pharmaceutical company employing 61,500 people worldwide and headquartered in Whitehouse Station, New Jersey, USA. Merck Sharp and Dohme Limited (MSD) is the UK subsidiary and employs approximately 1500 people, with a UK sales of £374 million in 2005. MSD is primarily concerned with the following therapeutic areas: High Blood Pressure, Migraine, HIV & AIDS, Osteoarthritis, Unstable Angina, Asthma, High Cholesterol, Benign Prostatic Hyperplasia, Rheumatoid Arthritis & Gout.

Top 50 pharmaceutical products:
Cozaar (10), Fosamax (24)

Other Merck Sharp & Dohme pharmaceutical products include:
ARCOXIA (etoricoxib), AGGRASTAT (tirofiban), COSOPT (dorzolamide plus timolol), COZAAR (losartan), COZAAR-Comp (losartan plus hydrochlorothiazide), CRIXIVAN (indinavir), EZETROL (ezetimibe Hypercholesterolaemia), FOSAMAX (alendronate), FOSAVANCE (alendronate), FOSAMAX ONCE-WEEKLY (alendronate), INVANZ (ertapenem), INEGY (ezetimibe plus simvastatin), MAXALT (rizatriptan), PRIMAXIN IM Injection (imipenum plus cilastatin), PRIMAXIN IV Injection (imipenum plus cilastatin), PROPECIA (finasteride), PROSCAR (finasteride), SINGULAIR (montelukast), TIMOPTOL (timolol), TRUSOPT (dorzolamide).

Merck Sharp & Dohme, further information:
www.merck.com, www.msd-uk.com

9. Lilly

Eli Lilly and Company is one the world's leading pharmaceutical corporations, employing 41,500 people worldwide of whom more than 8,000 are involved in research. Now entering it's 130th year in business, Eli Lilly and Company was founded in May 1876 by Colonel Eli Lilly in Indianapolis, USA, still home to the company's corporate headquarters. The company's primary therapeutic focus lies with: Sepsis, Cancer care, Diabetes management, Depression, Osteoporosis, Erectile Duysfunction, Stress urinary incontinence and Attention-deficit hyperactivity disorder.

Top 50 pharmaceutical products:
Zyprexa (6)

Lilly, further information:
www.lilly.com, www.lilly.co.uk

10. Johnson & Johnson

Johnson & Johnson is the world's most comprehensive and broadly based manufacturer of health care products and is located in New Brunswick, New Jersey, USA, where it was founded in 1886. Johnson & Johnson was named #6 on Fortune's 2006 Most Admired Companies list and ranked as the number one company in the annual survey's Pharmaceuticals category.

Top 50 pharmaceutical products:
Risperdal [Janssen Cilag] (33)

Johnson & Johnson, further information:
www.jnj.com

Other top 50 pharmaceutical products

Omeprazole [generic ](5), Simvastatin [generic] (7), Amlodipine [generic] (11), Symbicort [Akzo Nobel] (15), Co Codamol [generic] (17), Gabapentin [generic] (18), Ramipril [generic] (19), Xalatan [Pharmacia] (27), Alendronic [generic] (29), Citalopram [generic] (30), Risperdal [Janssen Cilag] (33), Flomax [Yamanouchi] (36)

British National Formulary

Compiled with the advice of clinical experts, this essential pharmaceutical product reference provides up-to-date guidance on prescribing, dispensing and administering medicines. The British National Formulary details medicines prescribed in the UK, with special reference to their uses, cautions, contraindications, side-effects, dosage and relative costs. Updated in print every six months, the British National Formulary reflects current best practice as well as legal and professional guidelines relating to the use of medicines.

Purchase British National Formulary online

The British Pharmacopoeia
by British Pharmacopoeia Commission

The British Pharmacopoeia is the authoritative, current collection of standards for UK medicinal substances and the official source of all UK quality standards. It is an essential reference for anyone involved in pharmaceutical Research and Development, manufacturing and testing, and plays a vital role in ensuring that all medicinal substances on the UK market meet standards of safety, quality and efficacy. The British Pharmacopoeia is supplied in a variety of formats designed for ease of use and a wide range of applications.

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