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Mayne Pharmaceutical


Mayne Pharmaceutical

Mayne Pharma Limited is focused on the development, manufacture, sale and distribution of medicines used by oncologists. The company is listed on the Australian Stock Exchange under the code “MYP”.

Mayne Pharma’s product portfolio has been built on world class process development capabilities in the two families of drugs that are commonly used in the treatment of cancer today: taxanes and platinum derivatives. The company has also expanded from its origins in generic chemotherapy medicines to related therapeutic drugs used by oncologists in the treatment of cancer such as antibiotics and pain management.

On the back of this expertise, Mayne Pharma has expanded from Australia so that it now distributes its products in more than 65 countries around the world. It has established strong commercial footholds especially in Europe and Asia Pacific. In North America, Mayne Pharma is the second largest supplier of generic, injectable oncology medicines in Canada and the company has a small and developing position in the United States that provides future opportunity to grow.

Mayne Pharma has increased its sales revenues significantly in the last three years on the back of acquisitions and internal growth. Pro-forma sales in its 2005 financial year were A$687 million up approximately 35% on the prior year.

In November 2005, Mayne Pharma was demerged from Mayne Group Limited so the business could focus on its core competencies and have increased flexibility to implement appropriate strategies and a capital structure that would help facilitate its continued success.

02/02/07: Hospira www.hospira.com has announced that it has completed the acquisition of Mayne Pharma, in the process creating the world's leading firm in speciality generic injectible pharmaceuticals. According to the terms of the transaction, the total value for the acquisition is AUD$2.6 billion (1.02 billion pounds), equating to an offer of AUD$4.10 per share to shareholders in Mayne Pharma. Following this acquisition, Hospira is implementing a new structure of leadership in order to establish a robust basis for growth in the future, augment its connection with customers and promote a stronger global perspective. To these ends, the company has appointed three regional presidents, two presidents focused on long-term growth and a corporate vice president of global strategy and business development. Christopher B Begley, chief executive officer of Hospira, said: "We are excited and confident about the growth opportunities this acquisition presents for all of our stakeholders." He added that the increased size of the company would enable it to reduce the overall costs of healthcare, resulting in an improvement in the financial strength of the healthcare system worldwide and enhanced affordability of care for patients. The Supreme Court of Victoria approved the scheme for the transaction of Mayne Pharma by a subsidiary of Hospira earlier this month. \

Mayne Pharmaceutical - Research & development

Mayne Pharma have proven expertise in solving drug delivery problems for patients and health professionals. Mayne Pharma pride themselves in being a customer-orientated company by continuing to develop products and services that meet their customers' needs for innovative drug delivery. The Mayne Pharma team of more than 200 scientists, chemists and regulatory affairs specialists are critical to the timely delivery of innovative new products. With more than US$20 million invested annually in product development, the Mayne Pharma product pipeline extends beyond five years and is focused on providing customers with innovation well into the future. mayne Pharma's drug delivery capabilities focus on developing innovative products with improved formulations, new dosage forms and simpler dosing schedules. Mayne Pharma will continue their development of innovative drug delivery technology, using in-house expertise, combined with collaborative development programs in association with academic and government research organisations. To support this vision, Mayne Pharma regularly partner with suppliers of active pharmaceutical ingredients to meet the challenge of developing generic pharmaceuticals. Mayne Pharma's global network of experienced regulatory affairs personnel enables them to achieve regulatory approvals faster than the pharmaceutical industry average.

Mayne Pharmaceutical - Manufacturing

Mayne Pharma is focused on developing a globally competitive supply chain through manufacturing products internally as well as strategically outsourcing some of its manufacturing requirements to reliable, high quality contract manufacturers.

Mayne Pharma manufactures pharmaceutical products in Australia, Germany and Puerto Rico for distribution to more than 65 countries around the world. Through a joint-venture with Zydus Cadila, we are also constructing a manufacturing facility in India that will produce cytotoxic anti-cancer agents when it is complete.

Mayne Pharma are capable of developing and manufacturing a wide variety of products to meet the increasingly diverse needs of our stakeholders globally. Mayne Pharma has the infrastructure and expertise to meet the requirements of each of the major regulatory authorities and to promptly secure product approvals.

Mayne Pharma's facilities are world-class and have been approved by the major authorities, including the FDA (USA), the MCA (United Kingdom), the HPFB (Canada) and the TGA (Australia).

Mayne Pharma's Mulgrave facility is its largest and most diverse finished dosage facility, with capabilities to formulate, fill, label and package finished dosage forms of injectable pharmaceutical products. Approximately A$50 million has been invested to establish a new cytotoxic production facility at Mulgrave that is expected to improve efficiency and be compliant with current Good Manufacturing Practice (cGMP) requirements. The new facility is expected to begin commercial production for Australia in 2006, with approvals for overseas markets expected to follow later in that year.

Mayne Pharma's Wasserburg facility in Germany can produce both terminally sterilized and aseptically filled ampoules and vials. The core competency of the business is lyophilization, a complex technique to freeze-dry a solution into a solid or powder to offer extended shelf life of the product.

The Aguadilla, Puerto Rico facility is currently going through an extensive upgrade and is expected to progressively recommence commercial production from around the middle of calendar year 2006. The Aguadilla facility will have the capability to formulate, fill, label and package finished dosage forms of injectable pharmaceutical products.

Mayne Pharma's joint venture with Zydus Cadila in India will almost double Mayne Pharma's cytotoxic manufacturing capabilities and assist with early development and launch of products at patent expiry in key target markets. The first products produced by the joint venture are expected to be launched in fiscal year 2008.

www.maynepharma.com

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